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The 7 Best Muscle Building Supplements of 2022 (Updated)

Amanda Kostro, RDN, LDN by Amanda Kostro, RDN, LDN
Jan 29, 2022
in FITNESS
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Are you trying to figure out what are the best supplements for muscle gain? Does it seem like no matter how many reps you do, how much weight you add to the barbells, or how many bodybuilding pills you take, you never make progress?

Or maybe you have the opposite problem: you feel chubby even while following a solid workout routine religiously. You can’t seem to convert fat to muscle.

Whatever your reason for arriving here, we can help you find the right supplements for muscle growth. Our team of fitness experts has researched and sifted through hundreds of different  supplements currently available on the market to help you select the very best.

In the two main sections below, you’ll find:

  • A quick overview of some of the most popular & effective gym supplements for muscle growth on the market
  • More detailed information to help you determine what’s best for you

The Ultimate Guide to the Best Supplements for Muscle Growth

To build muscle, your body needs certain building blocks. Without them, you can workout all you want, but your body won’t have the tools it needs to build muscle and you’ll stagnate.

Most of these building blocks can also be found in the foods you eat, like protein, calcium, magnesium, and glutamine. At least, they should be if you’re eating a complete diet, not a guarantee for most in today’s busy world.

How much of these compounds you need will also change when you’re building muscle, and your usual diet may not give you enough. This is where supplements can come in handy, filling in your nutritional gaps.

Below, we’ll outline all of the best supplements for muscle gain such as proteins, creatine, testosterone boosters, and more. With the research in hand, you’ll understand the important functions each offers so that you can build your own, unique regimen of bodybuilding supplements that will effectively address your needs.

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Proteins

casein protein powderAs mentioned, protein is essential for building muscle. If you are unable to consume the recommended amount of protein through diet alone, add protein powder for building muscle as a supplement.

This applies to nearly anyone hoping to gain muscle mass since it’s not easy to pack in nearly 100 grams of protein a day through chicken, legumes, and the egg diet alone.

Remember, depending on your goals, you should be consuming up to 1.3 grams of protein per kg of body weight. Protein powders are an easy way to reach your ideal dietary protein goals and are one of the top supplements for muscle building.

What are your options?

  • Whey Protein: This protein is a product of cheese making. Whey is the watery milk that’s separated and removed from the cheese curd. Through further processing, it’s turned into a powder. Whey protein is a great source of amino acids and nutrients. You can find whey protein from a number of manufacturers in different flavors including vanilla and chocolate.
Our recommendation: 100% Grass-Fed Whey Protein Isolate

Some protein powders are loaded with junk. We recommend this grass-fed protein isolate because it is a non-GMO product and contains no artificial sweeteners.

It is a US-based product, and the whey protein is cultivated from American cows. With 28 grams of protein in one scoop, one spoonful of this powder may provide the equivalent protein profile of a whole meal.

What’s even better is that one scoop is only 120 calories. This powder gives you quite a bit of protein for minimal calories, keeping you lean.

While protein supplements are not essential for everyone, a protein supplement may be needed for several reasons.

Here is a list of instances where someone would benefit from adding this whey protein supplement. Thinking about your needs, would you benefit from this product?

  • You don’t have time to eat a meal or snack within an hour after intense exercise
  • You are trying to keep your calories under control while still getting enough protein
  • You are vegetarian or vegan and may not be consuming enough protein

If you relate to any of the bullet points above, this whey protein supplement may be beneficial to reaching your fitness and dietary goals.

Protein supplements like this whey protein isolate can pack a lot of protein into one drink. Sometimes we may get tired of eating tons of meat, poultry and eggs to reach our protein goals!

Buy Whey Protein Here

When looking for a whey protein powder to purchase, seek out powders that offer at least 20 g of protein per serving (one scoop) and are low in carbohydrates (aim for 5 g per serving or less). You may run into whey protein isolate, which looks attractive because it’s a higher concentration of protein.

However, avoid this one as in the extreme processing, proteins are denatured that can render them less effective. In addition, these formulas are also often chock full of artificial sweeteners. Instead, look for powders from grass-fed cows that aren’t pumped with hormones.

  • Rice Protein: An alternative protein powder for muscle gain, rice protein is ideal for people who are lactose intolerant or have a milk allergy. As far as muscle gain and body composition when taken post-workout, this study showed that there was zero difference in outcomes when comparing taking whey protein and rice protein. So, if you prefer using rice protein, you can take it with confidence knowing that you’ll be able to achieve the same results you’d achieve if you were taking whey protein.

If you’re really interested in knowing the differences and investigate further, you’ll find that the amino acid profile does differ somewhat between rice and whey proteins. However, in effect, you still get everything you need from rice protein to build muscle.

How to Take It: Many people add a serving of protein powder to a milkshake or a delicious fruit smoothie. However, you can also add protein powder to pancakes, muffins and other items so that you can get a kick of protein without having it feel like a chore

You can take your protein at any time of day. However, it is important to take protein with some carbohydrates after a workout. So, if you’re looking for a quick and easy way to get your protein in, you can enjoy a protein shake after your workout. If you’re looking for protein powders for weight loss, check out top picks here.

What Fitness Experts Have to Say:

You’d have to look hard to find a fitness expert who doesn’t recommend taking supplemental protein powder for building muscle. It’s one of the best supplements for building muscle on the market!

In addition to serving as a muscle building supplement, protein powder can be the perfect complement to a successful weight loss plan. Studies show that the supplement can prevent loss of muscle mass, helping you lose fat exclusively instead.

Julian Shapiro, a fitness enthusiast and writer wrote an extensive guide to building muscle.  I asked him about his opinion on the best supplements for muscle gain. He said:

If I had to pick my favorite muscle building supplement, I’d pick protein. For both men and women, protein, either whey or rice, is the most effective and essential supplement for building muscle. Without this supplement, it’s hard to get enough protein in a day through food alone, making it difficult to reach your muscle building goals.

That said, Julian also recommends some of the other supplements included in this article, depending on what your goals are. A combination of carefully selected supplements based on your unique needs and goals is the best step you can take towards maximizing your muscle building power. Protein powder is very likely to be a part of that plan.

Creatine

man taking creatine for building muscleAnother top bodybuilders supplement, creatine is an amino acid found in the body. The highest levels of this molecule are in your muscles and brain.

It is made by your liver, pancreas and kidneys, but is also found in foods including meat, eggs and fish. Research has shown that it may help athletes including weightlifters who need short bursts of energy (5).

In this study, creatine monohydrate proved to be an effective muscle builder. It works to improve body composition, muscle mass, strength and power.  Note that it was also more effective than other forms of creatine. How does it do this?

Creatine helps create essential adenosine triphosphate (ATP). This is the energy source of muscle contractions. By upping your levels, you can increase the amount of energy available to your muscles, boosting your performance.

Because your muscle strength and size increases when you add weight and reps, improving your performance can be a game changer in terms of increasing your muscle mass. If you’re able to lift longer and harder, your muscles will grow. Creatine is certainly a winner among the best bodybuilding supplements.

Keep in mind that while creatine boosts your performance in the gym, helping you achieve better muscle building results, it is also associated with some side effects. One of the main concerns is that creatine may worsen or cause kidney problems.

Creatine shouldn’t be taken in combination with diabetes medications, acetaminophen, diuretics or caffeine. As always, speak with your doctor before taking supplements to make sure that the product is safe for you (6). Generally, for most people, the supplement is considered to be among the safer weight lifting supplements.

Our recommendation: Creatine HMB

Creatine by Transparent LabsCreatine is found in many protein supplements at baseline in the form of creatine monohydrate. If you take a protein supplement, you may already be getting creatine.

What makes this creatine so special? Like the protein supplement above, this creatine supplement contains no artificial sweeteners or dyes.

It contains 5000mg of creatine per dose and includes certain compounds to increase the bioavailability of the creatine, allowing it to be better absorbed.

As discussed, creatine increases muscle building and athletic performance via energy production. Still not sure if you should try this creatine supplement?

If you can relate to the following scenarios, you should talk to your doctor about adding this to your fitness routine:

  • You feel your workout could be enhanced with more energy
  • You have hit a plateau in your strength routine
  • You do not have health conditions or take medications/supplements that contraindicate the use of creatine

You may be wondering what conditions and medications contraindicate the use of creatine supplements. Creatine is contraindicated in people with kidney insufficiency or kidney disease.

If you take diabetes medication, diuretics or acetaminophen, do not take a creatine supplement. Use caution if you regularly consume caffeine while taking a creatine supplement.

Overall, if you are healthy and have gotten clearance from your doctor, consider this non-GMO creatine supplement.

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  • How to Take It: So, you want to give it a go? How much should you take and what should you look for in a supplement? Definitely opt for creatine monohydrate, as it performs better in studies than other varieties, as mentioned above. A standard dose is about 5 grams a day. You can try taking this muscle builder for about 4 weeks to boost your levels. Following this time, you can either cut out creatine or lower to a maintenance dose of 3-5 grams per day. However, you’ll notice if you read the fine print that subjects in studies often have a loading phase of five days where the dosage is upped to 20 g per day, prior to adopting a standard dose (7, 8).

You can add it to your protein shakes if you’re drinking those. That way you’ll get your supplements for muscle growth all at once.

What Fitness Experts Have to Say:

Creatine is quite popular among weightlifters and fitness enthusiasts. Antonis Damianou, a fitness coach, trainer, writer and founder of Myolean Fitness actually says creatine monohydrate is his number one choice in bodybuilding supplements. Here’s why:

  • “It’s the most well-researched ergogenic supplement, with over 1000 studies carried out on it.
  • It’s the most effective supplement for increasing high intensity performance and muscle hypertrophy.
  • Short and long term studies have shown no health risks associated with supplementation with creatine monohydrate.
  • It can potentially have positive health benefits in various clinical populations.
  • It’s extremely cheap.”

BCAAs (Branched-Chain Amino Acids)

BCAA capsules and in powder form.The Branched-Chain Amino Acids, BCAAs for short, are leucine, valine and isoleucine.  Essentially, its a form of protein powder for muscle gain or other uses.

These essential amino acids are not made by the body but are found in foods such as meats, dairy products and legumes.

In medicine, BCAAs are used for a number of conditions, however, for many uses, further research is necessary to determine whether or not treatment is effective.

Related to exercise and fitness, BCAAs are taken to help reduce muscle breakdown, which is why they may be known as supplements for muscle gain and strength.

Leucine, in particular, is known for playing an important role in muscle protein synthesis, which can help with muscle gain and maintenance. Some also claim that BCAAs can enhance performance, although many studies also refute this claim.

Despite the fact that BCAAs may offer some benefits, you should keep in mind that these three amino acids are also present in any quality whey protein that you purchase. You can also get these essential amino acids from food sources.

Basically, as long as you’re meeting your daily protein intake goals, you’re probably getting enough of these essential amino acids. Research supports this approach. So, why spend more on another supplement?

BCAAs may be the best choice to help curb muscle break down when exercising in a fasted state. As a muscle preserver, BCAAs are quite effective, even when your insulin levels are low.

Our recommendation: Intrasurge BCAA + Energy

Intrasurge BCAA EnergyThe Intrasurge supplement contains 3 BCAAs and caffeine for an extra boost during your workout, helping you work out harder. Since this is technically not a pre-workout supplement, be sure to take this with you to the gym and consume it during your workout.

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How to Take It: If you decide you want to take BCAAs as one of your weight lifting supplements, you can easily get them and take them much like you would protein powders.

One scoop provides 2.5g of leucine, 1.25g of isoleucine and 1.25g of valine. Take it before a workout, during or after. As with all supplementation, the aim is to reach your overall daily needs and goals.

What Fitness Experts Have to Say:

While some experts support the use of BCAAs, others argue that there are better muscle building supplements to spend your money on. In the end, it’s up to you. The experts I interviewed didn’t include this supplement among their recommended bodybuilding supplements.

Beta-alanine

beta alanine powderThis amino acid is actually produced by your body and so is considered a non-essential amino acid. However, in addition to taking it in supplement form, beta-alanine is also found in protein-heavy foods like meat and fish (9).

This amino acid has been linked to performance enhancement outcomes, especially for weightlifters. Studies show increased performance when taking this supplement.

How does it work? Beta-alanine plays a role in producing carnosine which is important for muscle endurance when exercising. By boosting carnosine levels, the muscles may be able to work for longer periods before growing tired.

In addition to enhancing your performance, beta-alanine may also help you increase your lean body mass. This is great for your muscle-building goals!

Our recommendation: Beta Alanine Powder

This beta alanine supplement from Bulk Supplements is 100% beta alanine. It is designed to be taken before a workout to prevent muscle fatigue during exercise.

Remember, however, your body can make its own beta alanine, and you can get beta alanine from food. Use this supplement to complement a well-rounded diet.

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How to Take It: In the studies mentioned above, amounts of 4-5g per day were taken by the subjects.

What Fitness Experts Have to Say:

While it’s not quite as popular as creatine and protein powders, beta-alanine is highly regarded by most fitness experts interviewed for this article as one of the quality muscle building supplements available on the market.

Citrulline Malate

Citrulline MalateCitrulline Malate is an amino acid also known as L-Citrulline and is taken for many different medical conditions.

There is some research that shows that the amino acid may help improve performance while exercising by reducing fatigue. What does that mean for you?

In your muscle building efforts, you can use this supplement to help you make it through longer, harder workouts. This will spur more muscle building in response to the trauma your muscles experience in a tough workout.

Not only that, but Citrulline Malate can also help reduce soreness after a workout. Who doesn’t want to avoid feeling sore? Reduced soreness means you can get back to the gym the next day with renewed enthusiasm.

Our recommendation: L-Citrulline Capsules

These Citrulline malate capsules from Nutricost are made primarily of only L-Citrulline itself. This is another supplement that can help delay the onset of fatigue during exercise.

Compared to some of the other supplements, these capsules do not contain caffeine, which may be desirable for someone who already consumes caffeine from other sources.

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How to Take It: Take this muscle growth supplement before your workout, ideally an hour before exercising. You should take about 6-8 g of the supplement.

What Fitness Experts Have to Say:

Another of the best muscle building supplements available,  most fitness experts highly recommend taking this supplement. The trainers interviewed for this article concur that it’s worth the investment.

Testosterone Boosters

testosterone boosters pills and supplementsYou now know that there are many factors involved in your body’s ability to build muscle. Hormones play a big role, particularly testosterone.

When it comes to the best workout supplements for men who are concerned about their testosterone levels, the supplements listed below are some of the most popular.

That being said, men aren’t the only ones who suffer from low testosterone levels. Women can also suffer from testosterone deficiency which can affect their overall well-being in addition to their sex drive.

If you’re a woman or man concerned about your testosterone levels, in addition to using supplements like the ones below, you should contact your doctor who will be able to diagnose any deficiencies and recommend additional treatments.

  • ZMA: This supplement is a combination of zinc, magnesium and vitamin B-6. Some research shows that this combination can help raise testosterone levels. In the trial, subjects took a daily dose of ZMA (which included 30 mg zinc monomethionine, 450 mg magnesium aspartate and 10.5 mg vitamin B-6) at night during 7 weeks. Other hormones like IGF also increased, while the stress hormone, cortisol was reduced, creating an overall more favorable hormone profile. Not surprisingly, muscle performance also improved. (n) This paper is surrounding in controversy, however, because one of the scientists involved also holds the trademark for ZMA, and the research is company-funded.

Other sources point out the fact that ZMA is only effective in men with zinc deficiencies, in which case it may help boost testosterone. For healthy men, there is no evidence of its effectiveness, the source claims.

Given the scare evidence and its lack of credibility, it’s difficult to recommend taking this supplement.

  • Tribulus Terrestris: A fruit from the Mediterranean, this supplement has been used in the Indian traditional medicine of Ayurveda. In addition to helping increase testosterone, many people take it to increase libido and as a cardioprotective aid. (10) Unfortunately, despite the fact that there are claims that tribulus terrestris can increase testosterone levels, studies don’t back up these claims.  There is some evidence, however, that it may improve athletic performance. If you want to choose one of the supplements for men, this should be your pick.
Our Recommendation: TestoFuel

TestoFuelIf you have been diagnosed with a certain testosterone deficiency, ask your doctor and/or pharmacist to see if TestoFuel could be beneficial for you.

Aside from balancing your testosterone, you may experience increased muscle strength while using this supplement during your intense exercise routine.

Here are certain instances where TestoFuel could help correct your testosterone problems:

  • You have hit a plateau and cannot identify the cause
  • You have been diagnosed with a testosterone deficiency and have received approval from your doctor to try this supplement
  • You consume a well-rounded diet and have confirmed that you do not currently have a deficiency in vitamin D

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What Fitness Experts Have to Say:

The experts interviewed for this article didn’t recommend either of these as reliable supplements for building muscle.

However, don’t despair over the poor reviews. There are other ways to achieve a testosterone booster for muscle gain. One of them is simply Vitamin D. A deficiency in this vitamin can lower your levels of testosterone.

Furthermore, you can get a very natural boost simply by weightlifting and engaging in HIIT (High Intensity Interval Training) exercise. In addition, you should avoid some foods like soy and alcohol which can lower testosterone levels (11). Through these natural solutions and lifestyle changes, you can influence your hormone profile, creating a balance that’s more favorable for muscle growth.

Gainers

Weight Gainers in Powder and Pill formIf you are underweight or have a naturally scrawny build, you may struggle to gain weight, let alone muscle mass, no matter what you do.

Eating at all hours of the day and night can be exhausting and require frequent trips to the grocery store. So you might find yourself asking, “What are the best supplements to gain weight”?

Unless you are overweight, you likely need to create a caloric surplus in order to gain muscle. With a weight gainer powder, you can supplement a healthy diet with the additional calories you need to gain weight in muscle.

Typically, gainers contain protein powder in the form of whey, casein or milk protein isolate. In addition, gainers include carbs and a smaller amount of fats.

You’ll want to choose a product that includes more than just simple sugars (dextrose) as the carbs. Some products include great sources of carbs such as oat flour, buckwheat or amaranth.

How to Take It: Take your gainer at any time of day as your objective is to reach overall calorie intake goals. Ideally, instead of using them as a meal substitute, you’ll use your gainer as a snack between high-calorie, healthy, balanced meals.

If you plan on taking protein powder for muscle growth in addition to gainers, make sure you add up all of your dietary protein intakes to make sure it’s worth the investment of taking both. You might be able to skip the plain protein powders.

What Fitness Experts Have to Say:

For “hard gainers”, Antonis Damianou recommends taking weight gain powders to help you meet your daily caloric goals. Add as much as you need after factoring in your meal plan for the day.

Looking for a Bulking-Up Capsule? Try Bulking Stack

The Muscle-building and Weight Gaining Capsule Package

Crazy Bulk Bulking StackGet those gains easily by taking Crazy Bulk’s stack. A stack is a few products that you take at the same time because they work well together.

This Crazy Bulk stack combines some powerful proteins to help you build more muscle along with testosterone boosting ingredients that will improve your performance and stimulate muscle growth. In addition, you’ll find other key ingredients like L-Citrulline in the stack which are key for improving your performance.

The more you lift and the longer you work, the more muscle you’ll build! Mimicking the assistance that steroids offer without the negative side effects, this stack is hard to beat.

Highlights

  • Features 4 products: D-Bal, Testo-Max, DecaDuro and Trenorol
  • Includes a free guide
  • 4 week supply
  • Combined with diet and heavy lifting, you’ll get great muscle
  • All products are taken as capsules

Nutrition Profile and Ingredients

  • D-Bal contains whey protein, L-Isoleucine, L-Valine, L-Leucine and Tribulus Terrestris
  • Testo-Max contains D-aspartic acid, among other ingredients, which has been shown to help increase testosterone levels in several studies (1,2)
  • DecaDuro’s main ingredients include Wild yam, L-Arginine and L-Citrulline. In particular the protein ingredients L-Arginine and L-Citrulline are known for their performance boosting properties. L-Citrulline has been shown to boost workout performance, allowing users to do more sets and reps that they could do otherwise.
  • Trenorol contains Beta Sitosterol, Samento Inner Bark, Nettle Leaf Extract and Pepsin. Both the samento inner bark and the nettle leaf extract may help reduce inflammation, improving your recovery time after workouts.

Who Makes It

Crazy Bulk is an American company known for its supplements. Featuring everything a gym-goer could need, the company offers performance enhancers and muscle builders alongside weight loss supplements as well.

This bulk company strives to offer natural alternatives to steroids that help natural bodybuilders achieve their goals. Featuring quality ingredients, GMP certified facilities and worldwide delivery, Crazy Bulk makes purchasing their supplements easy to do with confidence.

The Bottom Line

The combination of effects with this stack hits all major areas necessary for muscle building: additional proteins, performance enhancement tools and a testosterone boost. Take the stack for 4 or 8 weeks at a time and keep working out so that the benefits stick.

With this great combination of supplements, your investment will surely pay off in pure, hard muscle that you can wear with pride. Get that filled out, chiseled physique you’ve always wanted with the help of the Crazy Bulk bulking stack.

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The Best Pre Workout Supplements

While most of these gym supplements can be taken at any time of the day, some are best to include in your pre-workout routine. Citrulline malate, in particular, is one that should be taken about an hour ahead of your workout.

Because this supplement boosts performance, taking it ahead of your workout will maximize its effect, making sure you get the most out of the supplement.

Another supplement that’s ideal to take pre-workout is protein. Depending on your goals and your workout time, taking protein before your workout can help you keep your energy levels elevated while working out. Make sure you give yourself at least an hour between the time you take your protein and your workout time so that your body has time to digest.

Nitro Surge (Intense Energy and Razer-Focus)

Nitro Surge by Jacked FactoryThe NitroSurge pre-workout supplement by Jacked Factory aims to get you pumped and focused before a gym session. Besides L-Citrulline, this supplement also contains performance-enhancing betaine anhydrous and beta alanine.

It also contains L-theanine which has shown to inhibit nerve cell damage in one study.  For energy-boosting benefits, the NitroSurge is also equipped with caffeine and AstraGin for energy metabolism.

Before you buy, consider if you fall under the following circumstances in which this pre-workout would be beneficial to you:

  • You find yourself struggling with fatigue and sluggishness at the beginning of a workout
  • Consumption of this product does not make you exceed the daily recommendation of caffeine (Note: Current caffeine recommendations are no more than 400mg of caffeine per day for adults 19 and older)
  • Since this pre-workout does not contain protein, you must already be consuming a well-balanced diet (Do not use this supplement as a protein replacement)

If you try this product and aren’t completely “pumped” about it, try the Altius Pre-Workout by Jacked Factory.

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How to Take It: 

Per customer reports, some people experience a tingling sensation upon consumption of this product. As with any supplement, start off with a quarter or half dose to see how your body reacts.

What the Fitness Experts Have to Say:

According to researchers, caffeine-containing pre-workout supplements show greater gains in anaerobic power movements compared to placebo. Consult your doctor before using this type of product, however, especially if you have certain heart conditions.

What Factors Influence Muscle Gain?

Before getting into the nitty-gritty details about supplements, it’s important to have a good understanding of how muscle growth works. When you take a muscle growth supplement, the role it plays in helping you reach your goals should be very clear.

With the supplements available on the market, you can be sure that while some serve an important purpose, others are gimmicks. It’s easier to identify the money wasters if you know how muscle building works.

So, what makes muscles grow or fail to grow? It’s a combination of factors including:

What Makes Muscles Grow:

strong muscle man doing exerciseExercise

Arguably the most influential factor, exercise is what instigates muscle growth. When you exercise, especially if you engage in resistance training, it causes trauma to your muscles.

This is exactly what you want because it’s this trauma that triggers a response from your body that grows your muscles. To repair the injury or damage to your muscles, special cells called satellite cells arrive. Typically, your muscle fibers thicken and lengthen in this process. (1)

Exercise is highly effective in increasing your lean body mass, which is essentially muscle. In a study published in 2012, progressive resistance training helped men ages 50 to 83 gain an average of 2.4 pounds of lean body mass over an average of 20.5 weeks.

Progressive resistance training involves performing weight bearing exercises. In addition, you must slowly increase the challenge of the exercise over time by increasing the weight, reps and/or sets. Studies show that either increasing reps or weight amount will work. So, if you don’t want to lift more weight, you can just do more reps and still build muscle.

Diet

What you eat plays a big role in how much muscle your body can build. Proteins are especially important for building muscle. When you eat protein, your body breaks it down into amino acids which are the building blocks of muscle.

How much protein you should include in your diet depends on a number of factors including your age and muscle building goals. Older adults who engage in resistance training and those hoping for maximum muscle growth should eat 1 to 1.3 grams of protein per kg of body weight (2, 3).

If you weigh 150 lbs, that means you should take between 68 and 88 g of protein daily. Other recommendations are more modest, suggesting that .36 grams of protein per pound of body weight is enough.

bodybuilder eating healthy foods

However, protein isn’t everything. Contrary to popular belief, carbohydrates and calories from fats are also important. To gain muscle, people who are slender or scrawny need to create a calorie surplus in order to bulk up.

That means you need proteins and plenty of healthy carbs, vegetables and even some fats (think healthy fats like nuts, avocado, olive oil, etc.). Carbohydrates play a key role in building muscle.

This macronutrient has gotten a bad rap for making people fat. However, if you work out properly, eating plenty of carbs is in your best interest. After training, it’s ideal to ingest some carbs in combination with protein to help replenish your muscles’ glycogen stores.

Hormones

Several hormones play key roles in your body’s ability to build muscle. As you probably expected, testosterone makes the list. However, the growth hormone, and growth factors also have an influence. If you have any abnormal levels of these hormones, it could affect your ability to grow muscle and maintain muscle mass.

Recently, studies are coming out that show a general decline in testosterone levels of men in the United States and around the world. The trend is across the board and doesn’t appear to be caused simply by a decline in health, aging or an increase in obesity rates.

It could be caused because of chemicals or environmental factors. In any case, low levels of testosterone can affect many areas of your health, including your ability to build muscle. If you suspect that you have low testosterone levels, you can ask your doctor to test you for it.

In addition to traditional hormone therapies, there are also many natural ways to boost your levels including through supplements, some of which will be discussed later in this article.

Genetics

While they don’t play a big role, your body’s lean body mass and muscle strength is somewhat influenced by genetics. Actually, it’s good that they don’t have too much of an influence. Why? Because that means you have more of an influence on your muscle mass through your lifestyle.

You can control it! If genetics were a determining factor, there wouldn’t be much you could do to change your situation.

Age

body builder lifting dumbbellsOver time, we naturally lose muscle mass in a process called sarcopenia. On average, men lose about 30% of their muscle mass during their lives. Usually, this begins in your 30s and progresses slowly as you age.

But, don’t despair. You can rebuild and maintain muscle mass even as you age. Often, diet and exercise are enough. But, sometimes, if the above hormones play a role, your doctor may recommend medications and additional treatments (4).

Muscle growth is pretty straightforward. Through diet, exercise and ensuring your hormone levels are within the standards, you should be able to grow stronger and bigger.

But, is it really that easy?

No. It’s not easy for everyone to get the recommended amount of protein in their diets through good eating habits alone. Others may not have clinically low testosterone, but still benefit from boosting their levels to improve their muscle building capacity.

You can fix these common problems by finding the best supplements for building muscle. These easy to take pills and powders can also help you boost your performance at the gym which will, in turn, spur your body’s muscle building and recovery response.

Ready to learn about supplements? We’ll now cover some of the most popular supplements and how they contribute to muscle growth based on the above factors.

The Best Post Workout Supplements

Post workout, it’s important to restore your body’s energy by consuming protein and carbs. When you’re trying to build muscle, this is an especially important step. Protein powder is one of the best best post workout supplements and a great muscle builder for your post-workout routine, as long as you include a carbohydrate as well.

You can get this by eating a banana or adding oats or banana to your protein shake. Or simply cook up a batch of healthy oatmeal muffins and include protein powder in your recipe. Then, enjoy your post-workout supplement as a delicious snack!

There’s also evidence that shows that creatine is best-taken post-workout. So, if you’re planning on including creatine as one of your top muscle building pills, consider taking it post-workout for maximum benefits.

Be Smart with Your Supplements

Supplements for muscle growth can serve as a great tool for helping you increase your muscle mass.  Always remember that, as when taking any supplement, it’s best to consult with your doctor to ensure that you won’t face any adverse interactions with medications or negatively affect your health.

While the best supplements for muscle mass listed are all generally safe, individuals with chronic health conditions should be especially careful.

Remember that supplements for muscle gain should be part of a wider approach that includes lifestyle, exercise and diet. With a solid workout routine including weightlifting, a healthy, well-balanced diet and the inclusion of some of the best workout supplements, you should see results within a few months!

Have you successfully built up your muscle mass? How did you do it? What muscle building supplements did you use? Tell me about your experience in the comments.

 

Article Sources

  1. Kwon, Young sub M.S. and Len Kravitz, Ph.D. How do muscles grow? University of New Mexico, 2004.
  2. Preserve your muscle mass. Harvard Health Publishing, 19 February 2016.
  3. Chapman, Ivana. Why You’re Not Building Muscle. IvanaChapman.com, 14 December 2017.
  4. Sarcopenia With Aging. Compass by WebMD.
  5. Creatine Overview. Mayo Clinic.
  6. Watson, Stephanie. An Overview of Creatine Supplements. WebMD, 12 December 2020.
  7. Spillane, Mike et. al. The effects of creatine etyl ester supplementation combined with heavy resistance training on body composition, muscle performance, and serum and muscle creatine levels. The Journal of International Sports Medicine, February 2009.
  8. Shapiro, Julian. Building Muscle: How to Start. Julian.com.
  9. McMillen, Matt. Beta-Alanine. WebMD, 14 January 2021.
  10. Patel, Kamal. Tribulus terrestris. Examine, 1 June 2021.
  11. Cooper, Craig. How to Increase Testosterone Naturally. Prostate.net, 15 July 2021.
Amanda Kostro, RDN, LDN

Amanda Kostro, RDN, LDN

Amanda is a Registered Dietitian Nutritionist in Chicago who graduated with a bachelor's in Nutrition from Northern Illinois University. She completed her dietetic internship at Edward Hines Jr. VA Hospital in Hines, IL. Amanda has a background in clinical nutrition, nutrition education, and experience working with populations like children, acute care, intensive care, outpatients, and eating disorders. Amanda works with athletes and weight loss clients in the Los Angeles and southwestern Arizona area as a Dietitian. Amanda prides herself in connecting with her audience while providing evidenced-based information for a complex population.

Comments 16

  1. Reite says:
    4 years ago

    I used to play soccer for thirteen years. Quit a few years ago and just kept getting fatter. Blamed it on genetics at first, but its my own fault in the end. Go to the gym, eat well and stay active! I wasn’t a big fan of protein shakes etc at first, but it really helps speed up the process

  2. Lauren says:
    4 years ago

    Thanks for including alternatives for those of us who are lactose intolerant as whey protein is usually one of the only options I see being widely available. One of my New Years Resolutions is to workout more and gain my strength back, and I’ll definitely return to this post as a reference to research what will be the best option for me.

  3. Amanda Kostro, RDN, LDN says:
    4 years ago

    Luckily now a days there are so many protein options on the market. If you find that some protein powders give you discomfort, consider trying some plant-based protein powders that are made from soy, pea or wheat.

  4. Jason Torres says:
    4 years ago

    I get lost every time I walk into my neighborhood GNC… the people who work there know their stuff, but nobody knows my body better than me and that’s where it all falls apart, but I’m working on that. I agree, I rather have grass-fed and more natural options as opposed to anything containing GMO in the products… The point is to become healthier, not go the other way…. But I also don’t want to get too much soy in my diet either… My wife is doesn’t want it for me and it’s given me headaches too, so I’m not really one for those. I guess small amounts of soy should be okay, right? Could someone be allergic to soy? There’s tons of other options though and I’m going to have to really look more into these here coz it has everything I’ve been looking for! Thanks for putting this together!

  5. Amanda Kostro, RDN, LDN says:
    4 years ago

    I completely understand that you want supplements that will help, rather than hinder your health and progress. To find your specific needs, I would suggest seeing a Registered Dietitian so that they can help you determine what type of supplementation (if any) is needed. Dietitians can provide individualized recommendations.

    Some people do have allergies to soy, or they have an intolerance to soy. If you notice certain symptoms (like a headache) after soy consumption, you may have an intolerance. Discovering your food intolerances/allergies would also be handled by a Dietitian. For the general population who are not allergic/intolerant to soy, however, soy-based products can be a part of a healthy diet. New research has shown that soy is not harmful as people fear. If soy gives you issues, you could always opt for whey protein, pea protein or other forms of vegetable protein. Have you seen our article on protein powders? Click here.

  6. Grace says:
    4 years ago

    Thanks for creating this update. Your first few questions really hit the nail on the head. Out of so many options, how am I supposed to know what to choose? I’m glad I can find articles like this to help me do my research before-hand. Also, I’m wondering if there are adverse effects to taking testosterone as a woman?

  7. Amanda Kostro, RDN, LDN says:
    4 years ago

    I’m glad you found some good information from this article. For any of these supplements, I would suggest talking to your doctor and pharmacist. I would suggest thinking about why you are interested in taking testosterone. Are you looking to increase muscle size? Bulk up? Knowing your fitness goals will help you determine which products are appropriate for you.

  8. Rosie Shaw says:
    4 years ago

    Is it true that certain bodybuilding supplements like DNP have been linked to deaths? They should take such illegal bodybuilding and sports supplements off the market.

  9. Amanda Kostro, RDN, LDN says:
    4 years ago

    While I’m not well-versed in DNP, it is important to note that most supplements are not regulated by the FDA. The FDA has minimal standards for governing supplements before they make it to the shelves. All supplementation should be a case-by-case basis and under the discretion of a doctor and/or registered dietitian who knows your personal needs. Also, if you are consuming a well-rounded, healthy diet, supplementation may not be needed, even for making gains at the gym.

  10. Hafiz Khan says:
    4 years ago

    In the muscle building process, which way is the best one for quick results? A capsule shaped or the powder-shaped supplements?

  11. Ayo Joel says:
    3 years ago

    I like supplements even though I have not used them, but read how it’s work. I would like to get big muscles ? which bodybuilding supplements should I use?

  12. Minhaj says:
    3 years ago

    What I think is that Creatine and protein supplements are likely the most effective choices for muscle gain, but other supplements may be beneficial for certain people. And most importantly It’s very necessary to consult with your doctor before taking any supplement which you have already mentioned in your article?

  13. Javed says:
    3 years ago

    Is there any side effects of these supplements? If yes, then how can we avoid these side effects?

  14. Alex says:
    3 years ago

    Yes I understand Branched-chain amino acids are important for muscle growth. But they are found in many foods, so is it necessary to take supplement when you already consume enough protein?

  15. Rechelle says:
    3 years ago

    My Husband is always working out in the gym and he just started to take supplements?..How much time does it take to build muscular body with this supplements?, and does it have any side effect coz he have a hypertension..

  16. Lekgowa Mahole says:
    2 years ago

    Good evening,

    I would like buy good muscle building supplements. I would like you to recommend some for me. Kindly advice

    Thanks

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